Glycopolypeptide-Grafted Bioactive Polyionic Complex Vesicles (PICsomes) and Their Specific Polyvalent Interactions

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

EXTRACELLULAR VESICLES AND THEIR THERAPEUTIC APPLICATIONS: A REVIEW

Background & Aims: Extracellular vesicles are double phospholipid layer vesicles releasing from several cells.  These particles contain bio-molecules including mRNA, miRNA, DNA, proteins, and lipids which play a pivotal role in the cell to cell communication. Once delivered, they participate to change target cell function, fate, morphology, differentiation, and growth. The present study is a re...

متن کامل

Recent Advances in Engineering Polyvalent Biological Interactions

Polyvalent interactions, where multiple ligands and receptors interact simultaneously, are ubiquitous in nature. Synthetic polyvalent molecules, therefore, have the ability to affect biological processes ranging from protein-ligand binding to cellular signaling. In this review, we discuss recent advances in polyvalent scaffold design and applications. First, we will describe recent developments...

متن کامل

On the monomer density of grafted polyelectrolyte brushes and their interactions.

Most of the modern theories of grafted polyelectrolyte brushes are valid only for moderate stretching of the polyelectrolyte. However, particularly at low ionic strength and high grafting densities, even a moderate charge of the polyelectrolyte can generate a strong stretching. A simple mean field model for strongly stretched grafted polyelectrolyte brushes is suggested, based on an approximate...

متن کامل

Grafted block complex coacervate core micelles and their effect on protein adsorption on silica and polystyrene

We have studied the formation and the stability of grafted block complex coacervate core micelles (C3Ms) in solution and the influence of grafted block C3M coatings on the adsorption of the proteins beta-lactoglobulin, bovine serum albumin, and lysozyme. The C3Ms consist of a grafted block copolymer PAA(21)-b-PAPEO(14) (poly(acrylic acid)-b-poly(acrylate methoxy poly(ethylene oxide)), with a ne...

متن کامل

Novel drug carriers: from grafted polymers to cross-linked vesicles.

A simple and straightforward method of self-assembling grafted copolymers was developed to fabricate cross-linked polymer vesicles, which could conjugate anticancer drug cis-platinum and possess the capability of a high drug loading content, and a steady release rate.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: ACS Omega

سال: 2016

ISSN: 2470-1343,2470-1343

DOI: 10.1021/acsomega.6b00142